BDBM24941 (2Z)-2-{[(2,5-dibromophenyl)amino](hydroxy)methylidene}-3-oxobutanenitrile::CHEMBL228043::LFM-A13::Thr1 inhibitor, 2::alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide

SMILES: CC(=O)C(C#N)C(=O)Nc1cc(Br)ccc1Br

InChI Key: InChIKey=BQLDGDMKDYAGNE-UHFFFAOYSA-N

Data: 2 KI  15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 24941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (African clawed frog)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	22
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.67E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.81E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK3 (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK3 (Human)	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		7.20E+3	-6.94	6.10E+4	n/a	n/a	n/a	n/a	7.0	22
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Homoserine kinase (Escherichia coli (strain K12))	BDBM24941 (CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+4	-6.98	n/a	n/a	n/a	n/a	n/a	7.5	37
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