BDBM25391 CHEMBL200622::SB-590885::SB590885::[2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-5-(pyridin-4-yl)-1H-imidazol-2-yl}phenoxy)ethyl]dimethylamine

SMILES: CN(C)CCOc1ccc(cc1)-c1nc(c([nH]1)-c1ccc2C(CCc2c1)N=O)-c1ccncc1

InChI Key: InChIKey=ZLWRKMXLUCZVAR-UHFFFAOYSA-N

Data: 5 KI  1 IC50  3 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 25391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.300	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
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Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		0.160	-13.9	n/a	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM25391 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair