BDBM25470 N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide::cid_5056270::pyridine-thiazole, 1

SMILES: O=C(Nc1nc(cs1)-c1ccncc1)C1COc2ccccc2O1

InChI Key: InChIKey=QKKGSTFAKMXWFE-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 25470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 [1-543,T431N] (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20	n/a	n/a	n/a	n/a	7.0	22
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	637	n/a	n/a	n/a	n/a	7.3	22
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Serine/threonine-protein kinase MRCK alpha (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.85E+3	n/a	n/a	n/a	n/a	7.3	22
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.3	22
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	682	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<3.03	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate 1-dehydrogenase (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM25470 (cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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