BDBM25744 3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)phenyl]urea::US10383835, Compound 1555::US8501783, 1555::Urea-based compound, 25

SMILES: CC(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=UAKAZEQUWPXSOS-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 25744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epoxide hydrolase B (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	7.0	30
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Epoxide hydrolase 1 (Human)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
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Epoxide hydrolase (Horse)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epoxide hydrolase (Sheep)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Pig)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	201	n/a	n/a	n/a	n/a	n/a	n/a
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Epoxide hydrolase 1 (Cat)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
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Epoxide hydrolase 1 (Dog)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Human)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Mouse)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Human)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Human)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Human)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Rat)	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
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