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BDBM261578 US9708270, 73

SMILES: OCc1ccc(cc1N1CCC2(CCC(CC(O)=O)CC2)CC1)C(F)(F)F

InChI Key: InChIKey=HMWBUWHJFAXLKZ-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261578   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM261578
PNG
(US9708270, 73)
Show SMILES OCc1ccc(cc1N1CCC2(CCC(CC(O)=O)CC2)CC1)C(F)(F)F
Show InChI InChI=1S/C20H26F3NO3/c21-20(22,23)16-2-1-15(13-25)17(12-16)24-9-7-19(8-10-24)5-3-14(4-6-19)11-18(26)27/h1-2,12,14,25H,3-11,13H2,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 3.17E+3n/an/an/an/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
On the day before the measurement day, CHO cells expressing human GPR120 were plated at 10000 cells per well in a 384-well black plate (#3702, Cornin...


US Patent US9708270 (2017)


BindingDB Entry DOI: 10.7270/Q24B33B5
More data for this
Ligand-Target Pair