BDBM26226 (12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-1(10),2(7),3,5-tetraen-4-amine::A-987306

SMILES: [H][C@]12CCCC[C@@]1([H])C1=C(CCc3c(nc(N)nc13)N1CCNCC1)O2

InChI Key: InChIKey=DJKJVWJQAVGLHJ-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 26226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Rat)	BDBM26226 ((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	-11.5	n/a	n/a	n/a	n/a	n/a	7.4	25
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Histamine H4 receptor (Human)	BDBM26226 ((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...) Show SMILES Show InChI	GoogleScholar	UniChem		5.80	-11.2	n/a	n/a	n/a	n/a	n/a	7.4	25
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Histamine H3 receptor (Rat)	BDBM26226 ((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...) Show SMILES Show InChI	GoogleScholar	UniChem		13.5	-10.7	n/a	n/a	n/a	n/a	n/a	7.4	25
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Histamine H4 receptor (Human)	BDBM26226 ((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...) Show SMILES Show InChI	GoogleScholar	UniChem		79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM26226 ((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...) Show SMILES Show InChI	GoogleScholar	UniChem		933	-8.22	n/a	n/a	n/a	n/a	n/a	7.4	25
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Histamine H1 receptor (Human)	BDBM26226 ((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...) Show SMILES Show InChI	GoogleScholar	UniChem		3.55E+3	-7.43	n/a	n/a	n/a	n/a	n/a	7.4	25
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Histamine H2 receptor (Human)	BDBM26226 ((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...) Show SMILES Show InChI	GoogleScholar	UniChem		>9.12E+3	>-6.87	n/a	n/a	n/a	n/a	n/a	7.4	25
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					More data for this Ligand-Target Pair