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BDBM263455 (s)-2-(6-chloro-4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-(4-methoxyphenyl)ethyl)acetamide::US9556130, test 20

SMILES: COc1ccc(cc1)[C@H](C)NC(=O)Cn1nnc2ccc(Cl)cc2c1=O

InChI Key: InChIKey=IMHMUHMELFJCBS-LDGXTIHJNA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263455   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 139


(Homo sapiens (Human))
BDBM263455
PNG
((s)-2-(6-chloro-4-oxobenzo[d][1,2,3]triazin-3(4h)-...)
Show SMILES COc1ccc(cc1)[C@H](C)NC(=O)Cn1nnc2ccc(Cl)cc2c1=O
Show InChI InChI=1/C18H17ClN4O3/c1-11(12-3-6-14(26-2)7-4-12)20-17(24)10-23-18(25)15-9-13(19)5-8-16(15)21-22-23/h3-9,11H,10H2,1-2H3,(H,20,24)/t11-/s2
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
551 -7.93n/an/an/an/an/a7.44



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...


US Patent US9556130 (2017)


Article DOI: 10.1021/jm058205b
BindingDB Entry DOI: 10.7270/Q29025SJ
More data for this
Ligand-Target Pair