BDBM263481 (s)?n-(1-(4-methoxyphenyl)ethyl)-2-(4-oxo-6-(trifluoromethyl)benzo[d][1,2,3]triazin-3 (4h)-yl)acetamide::US10561662, Example 44::US11173161, EX 44::US9556130, test 44

SMILES COc1ccc(cc1)[C@H](C)NC(=O)Cn1nnc2ccc(cc2c1=O)C(F)(F)F

InChI Key InChIKey=FUWMUUAHZQTWMB-NSHDSACASA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263481   

TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263481((s)?n-(1-(4-methoxyphenyl)ethyl)-2-(4-oxo-6-(trifl...)
Affinity DataKi:  2.53E+3nM ΔG°:  -7.09kcal/molepH: 7.4 T: 2°CAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263481((s)?n-(1-(4-methoxyphenyl)ethyl)-2-(4-oxo-6-(trifl...)
Affinity DataKi:  2.53E+3nMAssay Description:Membranes were removed from −80° C., thawed and diluted in cold radioligand assay buffer (20 mM HEPES pH 7.4/5 mM MgCl2/1 mM CaCl2/Roche protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263481((s)?n-(1-(4-methoxyphenyl)ethyl)-2-(4-oxo-6-(trifl...)
Affinity DataKi:  2.53E+6nMAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent