BDBM263494 (s)-2-(8-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide::US10561662, Example 62::US11173161, EX 62::US9556130, test 62
SMILES COc1cccc2c1nnn(CC(=O)N[C@@H](C)c1ccc(OC(F)(F)F)cc1)c2=O
InChI Key InChIKey=RZIPXHMOCWWGGT-NSHDSACASA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 263494
Affinity DataKi: 240nM ΔG°: -8.39kcal/molepH: 7.4 T: 2°CAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Membranes were removed from −80° C., thawed and diluted in cold radioligand assay buffer (20 mM HEPES pH 7.4/5 mM MgCl2/1 mM CaCl2/Roche protea...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+5nMAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair