BDBM26392 2,4-diamino-5,6-disubstituted pyrimidine, 6::6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0.0^{2,7}]tetradeca-1(14),2,4,6,10,12-hexaen-4-amine

SMILES: CN1CCN(CC1)c1nc(N)nc-2c1CCc1ccccc-21

InChI Key: InChIKey=CEUMRIVIGREJGB-UHFFFAOYSA-N

Data: 6 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 26392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Human)	BDBM26392 (6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	295	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Rat)	BDBM26392 (6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	-11.3	n/a	n/a	n/a	n/a	n/a	7.4	25
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Histamine H4 receptor (Human)	BDBM26392 (6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0...) Show SMILES Show InChI	GoogleScholar	UniChem		15.5	-10.6	n/a	n/a	n/a	n/a	n/a	7.4	25
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Histamine H4 receptor (Human)	BDBM26392 (6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0...) Show SMILES Show InChI	GoogleScholar	UniChem		186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM26392 (6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0...) Show SMILES Show InChI	GoogleScholar	UniChem		9.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM26392 (6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0...) Show SMILES Show InChI	GoogleScholar	UniChem		9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM26392 (6-(4-methylpiperazin-1-yl)-3,5-diazatricyclo[8.4.0...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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