BDBM26511 BMCL193669 Compound 17::N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)benzamide::sultam hydroxyethylamine (HEA) derivative, 9e

SMILES: CCNc1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CC1)N1CCCCS1(=O)=O

InChI Key: InChIKey=AMVDNFIQANYLEW-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM26511 (N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	4.5	22
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Beta-secretase 2 (Human)	BDBM26511 (N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	4.5	22
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					More data for this Ligand-Target Pair
Cathepsin D (Human)	BDBM26511 (N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM26511 (N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	4.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 2 (Human)	BDBM26511 (N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin D (Human)	BDBM26511 (N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair