BDBM27890 8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl}amino)-5-oxo-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxamide::Pyrido[2,3-d]pyrimidin-5-one, 17a

SMILES: CN1CCN(CCc2ccc(Nc3ncc4c(n3)n(cc(C(N)=O)c4=O)-c3ccc4CCCc4c3)cc2)CC1

InChI Key: InChIKey=KLHJDCUHOKZNOP-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 27890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Human)	BDBM27890 (8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	22
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27890 (8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
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Tyrosine-protein kinase receptor UFO (Human)	BDBM27890 (8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	25
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High affinity nerve growth factor receptor [440-796] (Human)	BDBM27890 (8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	25
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Mast/stem cell growth factor receptor Kit (Human)	BDBM27890 (8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	25
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Insulin receptor (Human)	BDBM27890 (8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.20E+4	n/a	n/a	n/a	n/a	n/a	25
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM27890 (8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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