BDBM27895 8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl}amino)-5-oxo-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxamide::Pyrido[2,3-d]pyrimidin-5-one, 18a

SMILES: CONC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(CCN4CCN(C)CC4)cc3)ncc2c1=O

InChI Key: InChIKey=IUQURQCHOSRPJM-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 27895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Human)	BDBM27895 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27895 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Human)	BDBM27895 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [440-796] (Human)	BDBM27895 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM27895 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin receptor (Human)	BDBM27895 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair