BDBM27909 8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-methylpiperidin-4-yl)phenyl]amino}-5-oxo-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxamide::Pyrido[2,3-d]pyrimidin-5-one, 37

SMILES: CONC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(cc3)C3CCN(C)CC3)ncc2c1=O

InChI Key: InChIKey=FIJWNTPHEHDJQG-UHFFFAOYSA-N

Data: 6 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 27909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Human)	BDBM27909 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	22
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27909 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	25
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Tyrosine-protein kinase receptor UFO (Human)	BDBM27909 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	25
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High affinity nerve growth factor receptor [440-796] (Human)	BDBM27909 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	25
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Mast/stem cell growth factor receptor Kit (Human)	BDBM27909 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	25
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Insulin receptor (Human)	BDBM27909 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	25
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