BindingDB logo
myBDB logout

BDBM28034 4-[(4-phenylphenyl)amino]thieno[2,3-c]pyridine-2-carboxylic acid::thieno[2,3-c]pyridine, 3a

SMILES: OC(=O)c1cc2c(Nc3ccc(cc3)-c3ccccc3)cncc2s1

InChI Key: InChIKey=PJMDRNYVBADPKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28034   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 8


(Homo sapiens (Human))
BDBM28034
PNG
(4-[(4-phenylphenyl)amino]thieno[2,3-c]pyridine-2-c...)
Show SMILES OC(=O)c1cc2c(Nc3ccc(cc3)-c3ccccc3)cncc2s1
Show InChI InChI=1S/C20H14N2O2S/c23-20(24)18-10-16-17(11-21-12-19(16)25-18)22-15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12,22H,(H,23,24)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 140n/an/an/an/a7.522



Abbott Laboratories



Assay Description
The COT direct HTRF assay was carried out using biotin-MEK1 as a substrate. The reaction was carried out in black 96 half-well plates. At designated...


Bioorg Med Chem Lett 19: 1722-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.088
BindingDB Entry DOI: 10.7270/Q2VH5M4P
More data for this
Ligand-Target Pair