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BDBM2898 (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1,2,3,4-tetrahydroquinazolin-2-one::CHEMBL283619::DPC961

SMILES: FC(F)(F)[C@]1(NC(=O)Nc2ccc(Cl)cc12)C#CC1CC1

InChI Key: InChIKey=JJWJSIAJLBEMEN-UHFFFAOYSA-N

Data: 5 IC50

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 2898   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)		BDBM2898
PNG
(CHEMBL283619 | (4S)-6-chloro-4-(2-cyclopropylethyn...)		GoogleScholar
UniChem
n/an/a 32n/an/an/an/a8.237


TBA



Citation and Details
More data for this
Ligand-Target Pair
Reverse transcriptase/RNaseH


(Human immunodeficiency virus type 1)		BDBM2898
PNG
(CHEMBL283619 | (4S)-6-chloro-4-(2-cyclopropylethyn...)		GoogleScholar
UniChem
n/an/a 31n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Reverse transcriptase/RNaseH


(Human immunodeficiency virus type 1)		BDBM2898
PNG
(CHEMBL283619 | (4S)-6-chloro-4-(2-cyclopropylethyn...)		GoogleScholar
UniChem
n/an/a 31n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM2898
PNG
(CHEMBL283619 | (4S)-6-chloro-4-(2-cyclopropylethyn...)		GoogleScholar
UniChem
n/an/a 31n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Reverse transcriptase


(Human immunodeficiency virus type 1)		BDBM2898
PNG
(CHEMBL283619 | (4S)-6-chloro-4-(2-cyclopropylethyn...)		GoogleScholar
UniChem
n/an/a 32n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair