BDBM32006 1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinoline-2,7-dione::MLS000076121::SMR000013433::cid_650462

SMILES: Cn1c2cccc3C(=O)c4ccccc4-c(c(NCCO)c1=O)c23

InChI Key: InChIKey=JHRNUMVGSNJFOB-UHFFFAOYSA-N

Data: 8 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 32006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-alpha (Human)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.46E+3	n/a	n/a	n/a	n/a	7.4	23
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14-3-3 protein gamma (Human)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 4 (Human)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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Beta-lactamase (Pseudomonas aeruginosa)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-lactamase (Salmonella enterica subsp. enterica serovar Choler...)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	619	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-lactamase (Pseudomonas aeruginosa)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein LANA1 (HHV-8)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 5 (Human)	BDBM32006 (1-(2-Hydroxy-ethylamino)-3-methyl-3H-naphtho[1,2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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