BindingDB PrimarySearch

BDBM32203 8-quinolinol::CHEMBL310555::US10005735, Table 1.7::US12377086, Compound 31::US9394254, 6::cid_1923::oxine::quinolin-8-ol

SMILES: c1cc2cccnc2c(c1)O

InChI Key: InChIKey=MCJGNVYPOGVAJF-UHFFFAOYSA-N

Data: 3 KI 27 IC50 1 EC50

PDB links: 3 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 32203
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thermolysin (Bacillus thermoproteolyticus)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Botulinum neurotoxin type A (Clostridium botulinum)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 2 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 1 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Botulinum neurotoxin type A (Clostridium botulinum)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 1 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 2 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 2 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 1 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Indoleamine 2,3-dioxygenase 1 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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Heat shock protein HSP 90-alpha (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	7.4	23
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Metallo-beta-lactamase type 2 (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.34E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Glutaminyl-peptide cyclotransferase (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.08E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a
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Cholesterol side-chain cleavage enzyme, mitochondrial (Rat)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lanosterol synthase (Rat)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lanosterol synthase (Rat)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
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26S proteasome non-ATPase regulatory subunit 14 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Metallo-beta lactamase [126-247,M154L] (Klebsiella pneumoniae)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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VIM-2 type metallo-beta-lactamase (Pseudomonas aeruginosa)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Fructose-bisphosphate aldolase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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26S proteasome non-ATPase regulatory subunit 14 (Human)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Metallo-beta lactamase [126-247,M154L] (Klebsiella pneumoniae)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
VIM-2 type metallo-beta-lactamase (Pseudomonas aeruginosa)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Thermolysin (Bacillus thermoproteolyticus)	BDBM32203 (cid_1923 \| CHEMBL310555 \| 8-quinolinol \| quinolin-...) Show SMILES Show InChI	GoogleScholar	UniChem	2.14E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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