BDBM32756 2-furancarboxylic acid [5-amino-1-(4-fluorophenyl)sulfonyl-3-pyrazolyl] ester::CHEMBL245265::Furan-2-carboxylic acid 5-amino-1-(4-fluoro-benzenesulfonyl)-1H-pyrazol-3-yl ester::MLS000033900::SMR000014918::US11584714, Compound 44#::[5-amino-1-(4-fluorophenyl)sulfonylpyrazol-3-yl] furan-2-carboxylate::[5-azanyl-1-(4-fluorophenyl)sulfonyl-pyrazol-3-yl] furan-2-carboxylate::cid_647599::furan-2-carboxylic acid [5-amino-1-(4-fluorophenyl)sulfonyl-pyrazol-3-yl] ester

SMILES: Nc1cc(OC(=O)c2ccco2)nn1S(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=YHILZMQMDKTBFN-UHFFFAOYSA-N

Data: 2 KI  9 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 32756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	7.4	23
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Cathepsin B (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	6.8	23
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Cathepsin B (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Genome polyprotein (WNV)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin B (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor XII (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Kallikrein-5 (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	846	n/a	n/a	n/a	n/a	n/a	n/a
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Corticotropin-releasing factor-binding protein (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
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Cathepsin B (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mannan-binding lectin serine protease 2 (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mannan-binding lectin serine protease 2 (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM32756 (CHEMBL245265 | [5-amino-1-(4-fluorophenyl)sulfonyl...) Show SMILES Show InChI	GoogleScholar	UniChem		6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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