BDBM3567 CHEMBL328106::N-(4-bromophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035 Analog 67
SMILES COc1cc2ncnc(Nc3ccc(Br)cc3)c2cc1OC
InChI Key InChIKey=MCNVTWIIWNZMGB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 3567
Affinity DataIC50: 0.960nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0724nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair