BDBM40314 3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::3-(4-chlorophenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::3-(4-chlorophenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-quinone::3-(4-chlorophenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::MLS000523518::SMR000122591::US9073941, 603::cid_460749

SMILES: Cn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=UCEGDYDPOSBUTP-UHFFFAOYSA-N

Data: 16 IC50  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 40314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POsterior Segregation (Caenorhabditis elegans)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a
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Catenin beta-1/Transcription factor 7-like 2 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-(apurinic or apyrimidinic site) endonuclease (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosyl-DNA phosphodiesterase 2 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
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Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<40	n/a	n/a	n/a	n/a	7.0	n/a
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Dihydrolipoyl dehydrogenase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	7.0	n/a
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Protein RecA (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
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Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Photoreceptor-specific nuclear receptor (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
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G-protein coupled receptor 55 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mothers against decapentaplegic homolog 3 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a
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Glycoprotein 42 (HHV-4)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
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3C-like protease (Avian infectious bronchitis virus)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Transitional endoplasmic reticulum ATPase (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Transitional endoplasmic reticulum ATPase (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 2 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	634	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 2 (Human)	BDBM40314 (3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	996	n/a	n/a	n/a	n/a	n/a	n/a
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