BDBM43201 (2Z,4S,6S,12aS)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-2-[hydroxy-(1-pyrrolidinylmethylamino)methylidene]-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione::(2Z,4S,6S,12aS)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-2-[hydroxy-(pyrrolidin-1-ylmethylamino)methylidene]-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione::(2Z,4S,6S,12aS)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-2-[hydroxy-(pyrrolidinomethylamino)methylene]-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione::(2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11,12a-tetrakis(oxidanyl)-2-[oxidanyl-(pyrrolidin-1-ylmethylamino)methylidene]-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione::MLS000028710::ROLITETRACYCLINE::SMR000058701::cid_6420073

SMILES: CN(C)[C@H]1C2CC3C(C(=O)c4c(O)cccc4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)C(C(=O)NCN2CCCC2)C1=O

InChI Key: InChIKey=PLDZOHPIBZVDLQ-UHFFFAOYSA-N

Data: 1 IC50  8 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 43201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a
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Glutathione S-transferase Mu 1 (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a
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Bcl-2-like protein 10 [11-204] (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 8 (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.06E+3	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 7 (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.35E+3	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 19 (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.53E+3	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 16 (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.31E+3	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 4 gamma 1 (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 4 (Human)	BDBM43201 ((2Z,4S,6S,12aS)-4-(dimethylamino)-6-methyl-6,10,11...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a
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