BDBM43524 4-(4-fluorophenyl)-2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidine::4-(4-fluorophenyl)-2-mesyl-6-(trifluoromethyl)pyrimidine::4-(4-fluorophenyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine::MLS000675919::SMR000297077::US11725000, Compound 45::cid_2987363

SMILES: CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccc(F)cc1

InChI Key: InChIKey=FABYEEIARBZBHO-UHFFFAOYSA-N

Data: 10 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 43524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 1-alpha/beta (Human)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Signal transducer and activator of transcription 3 [702-738,740-752] (Human)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA damage-inducible transcript 3 protein (Mouse)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
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X-box-binding protein 1 (Human)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA damage-inducible transcript 3 protein (Mouse)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Toll-like receptor 9 (Human)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-lactamase (Pseudomonas aeruginosa)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-lactamase (Pseudomonas aeruginosa)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Galanin receptor type 3 (Human)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (Human)	BDBM43524 (SMR000297077 | MLS000675919 | 4-(4-fluorophenyl)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
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