BDBM449844 1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifluoromethoxy)ethyl]benzimidazol-5-yl]pyridin-2-one ::US10703740, Compound 1::US11365186, Compound 1

SMILES: CC1=CC(=CN(C1=O)C)c2ccc3c(c2)n(c(n3)C4CCOCC4)CCOC(F)(F)F

InChI Key: InChIKey=KPWWFNXRLAAREN-UHFFFAOYSA-N

Data: 2 IC50  5 Kd

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 449844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Human)	BDBM449844 (1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 [49-170] (Human)	BDBM449844 (1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 2 (Human)	BDBM449844 (1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 3 (Human)	BDBM449844 (1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 (Human)	BDBM449844 (1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a
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Histone acetyltransferase p300 (Human)	BDBM449844 (1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
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CREB-binding protein (Human)	BDBM449844 (1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
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