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BDBM4891 3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::3-[4-Methyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]propionic Acid::3-substituted indolin-2-one 11e::SU5402 analog 11e
SMILES: Cc1c(CCC(O)=O)c[nH]c1\C=C1/C(=O)Nc2cc(ccc12)-c1ccccc1
InChI Key: InChIKey=CEFJMJRPRONXNH-UHFFFAOYSA-N
Data: 4 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 (Human) | BDBM4891![]() (3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...) | GoogleScholar | UniChem | n/a | n/a | 300 | n/a | n/a | n/a | n/a | 7.5 | 22 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Fibroblast growth factor receptor 1 (Human) | BDBM4891![]() (3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...) | GoogleScholar | UniChem | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Platelet-derived growth factor receptor beta (Human) | BDBM4891![]() (3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...) | GoogleScholar | UniChem | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor (Human) | BDBM4891![]() (3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||