BDBM50004659 CHEMBL321808::[2-(5-Dimethylaminomethyl-furan-2-ylmethylsulfanyl)-ethyl]-(4-nitro-pyridazin-3-yl)-amine
SMILES CN(C)Cc1ccc(CSCCNc2nnccc2[N+]([O-])=O)o1
InChI Key InChIKey=YSANROTYHBNTDV-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50004659
Affinity DataIC50: 600nMAssay Description:Binding affinity of the compound against mouse Muscarinic acetylcholine receptor M2 using heart tissue and [3H]-N-methylscopolamineMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:In vitro acetyl cholinesterase(AChE-I) inhibitory activity of the compound to determine its ability to reverse the cholinergic deficit characteristic...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of South Carolina
Curated by ChEMBL
University Of South Carolina
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate preincubated for 8 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro Butyrylcholinesterase inhibitory activity of the compound to determine its ability to reverse the cholinergic deficit characteristic of ADMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate preincubated for 8 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University of South Carolina
Curated by ChEMBL
University of South Carolina
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Binding affinity of the compound against mouse Muscarinic acetylcholine receptor M1 using cerebral cortex and [3H]-pirenzepineMore data for this Ligand-Target Pair