BDBM50007676 4-Benzyl-1-phenethyl-piperidine::CHEMBL18222::CHEMBL553596

SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=FKVJGSPOLUAUNN-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50007676   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007676(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Affinity DataKi:  22nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007676(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Affinity DataKi:  1.76E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50007676(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibitory activity against recombinant human Chemokine receptor type 3 (CCR3) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007676(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Affinity DataIC50:  347nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Of Oregon

Curated by ChEMBL
LigandPNGBDBM50007676(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Affinity DataIC50: >1.00E+5nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2C NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University Of Oregon

Curated by ChEMBL
LigandPNGBDBM50007676(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Affinity DataIC50: >1.00E+5nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing 1A/2A NMDA receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Of Oregon

Curated by ChEMBL
LigandPNGBDBM50007676(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Affinity DataIC50:  1.10E+3nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50007676(4-Benzyl-1-phenethyl-piperidine | CHEMBL18222 | CH...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against human Chemokine receptor type 1 expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed