BDBM50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514

SMILES: Oc1cc2CCNCC(c3ccccc3)c2cc1O

InChI Key: InChIKey=JUDKOGFHZYMDMF-UHFFFAOYSA-N

Data: 22 KI  4 IC50  4 Kd  12 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 50004923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POsterior Segregation (Caenorhabditis elegans)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a
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D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Adenylate cyclase type 1 (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2C adrenergic receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.35E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	386	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	386	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	140	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	248	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		26.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		248	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		393	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		6.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		6.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50004923 (CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair