BDBM50009719 7-Methyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine::CHEMBL296725::L-158338

SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=CYUMNDVYHILLEX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50009719   

TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009719(7-Methyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II type 1-AT1 receptor determined as its ability to displace 125I-Sarl,Ile8-AII from th...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor B(RAT)
Università

Curated by ChEMBL
LigandPNGBDBM50009719(7-Methyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  1nMAssay Description:Binding affinity for rat angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Exploratory Chemistry Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009719(7-Methyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  1nMAssay Description:Binding affinity towards Angiotensin receptor from rabbit aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009719(7-Methyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009719(7-Methyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from AT2 receptor in rat midbrain m...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009719(7-Methyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II receptor, type 2 determined as its ability to displace 125I-Sarl,Ile8-AII from the r...More data for this Ligand-Target Pair
In DepthDetails Article