BDBM50011032 5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide::Atorvastatin lactone::CHEMBL333687::US9006282, Example 3, Compound 2

SMILES: CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1

InChI Key: InChIKey=OUCSEDFVYPBLLF-UHFFFAOYSA-N

Data: 2 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50011032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.2	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B1 (Human)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Rat)	BDBM50011032 (CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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