BDBM50029367 CHEMBL3343309

SMILES CN1CCN(CCCOc2ccc3c(Nc4ccc(NC(=O)NCc5ccccc5)cc4)ncnc3c2)CC1

InChI Key InChIKey=HMYRVBUHXWGRJY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 80 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029367   

TargetAurora kinase B(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50029367(CHEMBL3343309)
Affinity DataIC50:  289nMAssay Description:Inhibition of Aurora-B (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50029367(CHEMBL3343309)
Affinity DataIC50:  195nMAssay Description:Inhibition of Aurora-A (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed