BDBM50036844 2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl}-isoindole-1,3-dione; compound with oxalic acid::CHEMBL52396

SMILES CCCN(CCCCN1C(=O)c2ccccc2C1=O)C1COc2cccc(OC)c2C1

InChI Key InChIKey=ISIUTFCGQWDGHC-UHFFFAOYSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50036844   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  50nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  400nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  4.00E+4nMAssay Description:Binding affinity towards dopamine receptor D1 in calf striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  50nMAssay Description:The compound was evaluated for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))TBA
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  400nMAssay Description:The compound was evaluated for its ability to displace [3H]5-HT from 5-hydroxytryptamine 1B receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails
TargetSerotonin 2 (5-HT2) receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails
TargetD(2) dopamine receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  30nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed