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BDBM50040151 7,9-Dimethyl-5-phenylsulfanyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::CHEMBL435263

SMILES: C[C@@H]1C[C@H]2[C@@H](Cc3c(Sc4ccccc4)[nH]c4cccc2c34)N(C)C1

InChI Key: InChIKey=FVVUBLWTATZKEN-WIBUTAKZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040151   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DRD2


(BOVINE)		BDBM50040151
PNG
(7,9-Dimethyl-5-phenylsulfanyl-4,6,6a,7,8,9,10,10a-...)
Show SMILES C[C@@H]1C[C@H]2[C@@H](Cc3c(Sc4ccccc4)[nH]c4cccc2c34)N(C)C1
Show InChI InChI=1S/C22H24N2S/c1-14-11-17-16-9-6-10-19-21(16)18(12-20(17)24(2)13-14)22(23-19)25-15-7-4-3-5-8-15/h3-10,14,17,20,23H,11-13H2,1-2H3/t14-,17-,20-/m1/s1
UniProtKB/SwissProt

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n/an/a 180n/an/an/an/an/an/a



Lilly Research Centre Ltd.

Curated by ChEMBL


Assay Description
Competition in vitro with the dopamine receptor D2 anatagonist [3H]-spiperone, for binding sites on calf caudate membranes.

J Med Chem 36: 912-8 (1993)


Article DOI: 10.1021/jm00059a017
BindingDB Entry DOI: 10.7270/Q2FJ2FT2
More data for this
Ligand-Target Pair