BDBM50041314 (E)-2-(pyridin-4-ylmethylene)-2,3-dihydroinden-1-one::2-[1-Pyridin-4-yl-meth-(E)-ylidene]-indan-1-one::CHEMBL23150

SMILES O=C1\C(Cc2ccccc12)=C\c1ccncc1

InChI Key InChIKey=UFLITIQLRTXBDW-UKTHLTGXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041314   

TargetAromatase(Homo sapiens (Human))
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50041314((E)-2-(pyridin-4-ylmethylene)-2,3-dihydroinden-1-o...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human Placental Cytochrome P450 19A1 in vitro using human placental microsomes and testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50041314((E)-2-(pyridin-4-ylmethylene)-2,3-dihydroinden-1-o...)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of TNFalpha (unknown origin)-induced adhesion of BCECF fluorescence-labeled human U937 cells to human HT-29 cells measured at 3 hrs post T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50041314((E)-2-(pyridin-4-ylmethylene)-2,3-dihydroinden-1-o...)
Affinity DataIC50:  2.13E+3nMAssay Description:Inhibition of TNFalpha (unknown origin)-induced adhesion of BCECF fluorescence-labeled human U937 cells to human HT-29 cells measured at 3 hrs post T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed