BDBM50042987 (E)-1-(2,4-Dihydroxy-phenyl)-3-phenyl-propenone::(E)-1-(2,4-dihydroxyphenyl)-3-phenylprop-2-en-1-one::(E)-2',4'-dihydroxychalcone::1-(2,4-Dihydroxy-phenyl)-3-phenyl-propenone::1-(2,4-dihydroxyphenyl)-3-phenylprop-2-en-1-one (4)::2',4'-Dihydroxychalcone::CHEMBL105310
SMILES Oc1ccc(C(=O)\C=C\c2ccccc2)c(O)c1
InChI Key InChIKey=JUMSUVHHUVPSOY-RMKNXTFCSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50042987
Affinity DataIC50: 1.10E+5nMpH: 6.8 T: 2°CAssay Description:All compounds were dissolved in DMSO (final DMSO concentration in test solution was 2.0%). Phosphate buffer, pH 6.8, was use to dilute the DMSO stoc...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 4.00E+5nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 2.49E+7nMAssay Description:Inhibition of P-gp in human HK2 cells assessed as Rhodamine-123 accumulation by fluorescence assayMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Guangxi Medical University
Curated by ChEMBL
Guangxi Medical University
Curated by ChEMBL
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair