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BDBM50043890 1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL8589

SMILES: COc1ccc2C(CCCN3CCNCC3)=CCCc2c1

InChI Key: InChIKey=OQFOIKSARZMXEY-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043890   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50043890
PNG
(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Show SMILES COc1ccc2C(CCCN3CCNCC3)=CCCc2c1
Show InChI InChI=1S/C18H26N2O/c1-21-17-7-8-18-15(4-2-5-16(18)14-17)6-3-11-20-12-9-19-10-13-20/h4,7-8,14,19H,2-3,5-6,9-13H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Università di Bari

Curated by ChEMBL


Assay Description
In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortex


J Med Chem 37: 99-104 (1994)


Article DOI: 10.1021/jm00027a012
BindingDB Entry DOI: 10.7270/Q2NP23GP
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50043890
PNG
(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Show SMILES COc1ccc2C(CCCN3CCNCC3)=CCCc2c1
Show InChI InChI=1S/C18H26N2O/c1-21-17-7-8-18-15(4-2-5-16(18)14-17)6-3-11-20-12-9-19-10-13-20/h4,7-8,14,19H,2-3,5-6,9-13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Università di Bari

Curated by ChEMBL


Assay Description
Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranes


J Med Chem 37: 99-104 (1994)


Article DOI: 10.1021/jm00027a012
BindingDB Entry DOI: 10.7270/Q2NP23GP
More data for this
Ligand-Target Pair