BDBM50046268 6-Bromomethylene-3-naphthalen-1-yl-tetrahydro-pyran-2-one::6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tetrahydro-pyran-2-one::BTNP::CHEMBL6206

SMILES Br\C=C1/CCC(C(=O)O1)c1cccc2ccccc12

InChI Key InChIKey=BYUCSFWXCMTYOI-ZRDIBKRKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046268   

Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50046268(6-Bromomethylene-3-naphthalen-1-yl-tetrahydro-pyra...)
Affinity DataIC50:  140nMAssay Description:Compounds were evaluated for the inhibitory activity against canine myocardial cytosolic calcium dependent phospholipase A2 .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50046268(6-Bromomethylene-3-naphthalen-1-yl-tetrahydro-pyra...)
Affinity DataIC50: >100nMAssay Description:Compounds were evaluated for the inhibitory activity against canine myocardial cytosolic calcium dependent phospholipase A2 .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50046268(6-Bromomethylene-3-naphthalen-1-yl-tetrahydro-pyra...)
Affinity DataIC50:  800nMAssay Description:Inhibition of FAAH in rat brain assessed as hydrolysis of anandamideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50046268(6-Bromomethylene-3-naphthalen-1-yl-tetrahydro-pyra...)
Affinity DataIC50:  800nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed