BDBM50046732 (R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL81525

SMILES: COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2

InChI Key:

Data: 8 KI  17 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50046732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		3.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES Show InChI	GoogleScholar	UniChem		4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair