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BDBM50055265 2-(1H-Indol-3-yl)-N-(4-methoxy-benzyl)-2-oxo-acetamide::2-(1H-indol-3-yl)-N-(4-methoxybenzyl)-2-oxoacetamide::CHEMBL306310

SMILES: COc1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1

InChI Key: InChIKey=STQWWORVIGBLOE-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50055265   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)


(Rattus norvegicus (Rat))
BDBM50055265
PNG
(2-(1H-Indol-3-yl)-N-(4-methoxy-benzyl)-2-oxo-aceta...)
Show SMILES COc1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1
Show InChI InChI=1S/C18H16N2O3/c1-23-13-8-6-12(7-9-13)10-20-18(22)17(21)15-11-19-16-5-3-2-4-14(15)16/h2-9,11,19H,10H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
195n/an/an/an/an/an/an/an/a



Universita di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]flumazenil from rat GABA-Aalpha1beta2gamma2 receptor expressed in HEK293 cells


J Med Chem 52: 3723-34 (2009)


Article DOI: 10.1021/jm9001154
BindingDB Entry DOI: 10.7270/Q2N58M89
More data for this
Ligand-Target Pair
GABA(A) receptor subunit alpha-2


(Rattus norvegicus (Rat))
BDBM50055265
PNG
(2-(1H-Indol-3-yl)-N-(4-methoxy-benzyl)-2-oxo-aceta...)
Show SMILES COc1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1
Show InChI InChI=1S/C18H16N2O3/c1-23-13-8-6-12(7-9-13)10-20-18(22)17(21)15-11-19-16-5-3-2-4-14(15)16/h2-9,11,19H,10H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.95E+3n/an/an/an/an/an/an/an/a



Universita di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]flumazenil from rat GABA-Aalpha2beta2gamma2 receptor expressed in HEK293 cells


J Med Chem 52: 3723-34 (2009)


Article DOI: 10.1021/jm9001154
BindingDB Entry DOI: 10.7270/Q2N58M89
More data for this
Ligand-Target Pair