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BDBM50062892 2-(Acetyl-methyl-amino)-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide::CHEMBL346718

SMILES: CN(CC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl)C(C)=O

InChI Key: InChIKey=ACPMOXVLJKNTRY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062892   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062892
PNG
(2-(Acetyl-methyl-amino)-N-[3-(3-bromo-2-methyl-imi...)
Show SMILES CN(CC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl)C(C)=O
Show InChI InChI=1S/C21H21BrCl2N4O3/c1-12-20(22)28-9-5-6-17(21(28)25-12)31-11-14-15(23)7-8-16(19(14)24)27(4)18(30)10-26(3)13(2)29/h5-9H,10-11H2,1-4H3
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Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair