BDBM50067929 4-(2-{[(E)-3-(4-Dimethylcarbamoyl-phenyl)-acryloylamino]-methyl}-pyrrol-1-yl)-N*1*,N*1*,N*3*,N*3*-tetramethyl-2-(2-methyl-quinolin-8-yloxymethyl)-isophthalamide; hydrochloride::CHEMBL537683

SMILES CN(C)C(=O)c1ccc(\C=C\C(=O)NCc2cccn2-c2ccc(C(=O)N(C)C)c(COc3cccc4ccc(C)nc34)c2C(=O)N(C)C)cc1

InChI Key InChIKey=GTHGGSLNYNOZTO-CJLVFECKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067929   

TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067929(4-(2-{[(E)-3-(4-Dimethylcarbamoyl-phenyl)-acryloyl...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of the specific binding of [3H]BK to human recombinant Bradykinin receptor B2 expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067929(4-(2-{[(E)-3-(4-Dimethylcarbamoyl-phenyl)-acryloyl...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed