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BDBM50069816 4-((3R,4R)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole::4-((3R,4R)-4-methylpyrrolidin-3-yl)-1H-imidazole::CHEMBL313127::SCH-50971

SMILES: C[C@H]1CNC[C@@H]1c1cnc[nH]1

InChI Key: InChIKey=KTEPQLOOQDLKHF-WZTWBHKBNA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069816   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HRH3


(GUINEA PIG)
BDBM50069816
PNG
(4-((3R,4R)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole ...)
Show SMILES C[C@H]1CNC[C@@H]1c1cnc[nH]1
Show InChI InChI=1/C8H13N3/c1-6-2-9-3-7(6)8-4-10-5-11-8/h4-7,9H,2-3H2,1H3,(H,10,11)/t6-,7-/s2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
2.30n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor


Bioorg Med Chem Lett 8: 243-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00020-1
BindingDB Entry DOI: 10.7270/Q2ST7P0Z
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50069816
PNG
(4-((3R,4R)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole ...)
Show SMILES C[C@H]1CNC[C@@H]1c1cnc[nH]1
Show InChI InChI=1/C8H13N3/c1-6-2-9-3-7(6)8-4-10-5-11-8/h4-7,9H,2-3H2,1H3,(H,10,11)/t6-,7-/s2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound to H-1 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine ligand


Bioorg Med Chem Lett 8: 243-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00020-1
BindingDB Entry DOI: 10.7270/Q2ST7P0Z
More data for this
Ligand-Target Pair