BDBM50074372 (2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-morpholin-4-yl-pyrimidin-2-yl)-amine::CHEMBL432496

SMILES CCN(c1nc(C)cc(n1)N1CCOCC1)c1ccc(cc1Br)C(C)C

InChI Key InChIKey=DQSVEQFHEZHQRX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074372   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074372((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-mor...)
Affinity DataKi:  22nMAssay Description:Binding affinity for human recombinant corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074372((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-mor...)
Affinity DataKi:  22nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074372((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-mor...)
Affinity DataKi:  63nMAssay Description:Compound was tested for the inhibition of binding of the radioligand, [125 I-Tyr0]-CRF to rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed