BDBM50074987 CHEMBL113502::N-[2-Cyano-4-methoxy-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-2-(3-ethyl-ureido)-N-methyl-acetamide

SMILES CCNC(=O)NCC(=O)N(C)c1ccc(OC)c(COc2cccc3ccc(C)nc23)c1C#N

InChI Key InChIKey=GSMWKYQZPCPTFR-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074987   

TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074987(CHEMBL113502 | N-[2-Cyano-4-methoxy-3-(2-methyl-qu...)
Affinity DataKi:  6nMAssay Description:Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074987(CHEMBL113502 | N-[2-Cyano-4-methoxy-3-(2-methyl-qu...)
Affinity DataEC50:  450nMAssay Description:Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074987(CHEMBL113502 | N-[2-Cyano-4-methoxy-3-(2-methyl-qu...)
Affinity DataIC50:  54nMAssay Description:Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed