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BDBM50081144 3-(3,5-Dimethyl-phenyl)-7-methyl-4-(1-methyl-piperidin-3-ylmethoxy)-1H-quinolin-2-one::CHEMBL91311

SMILES: CN1CCCC(COc2c(-c3cc(C)cc(C)c3)c(=O)[nH]c3cc(C)ccc23)C1

InChI Key: InChIKey=BEXKROPOOFFEPG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081144   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50081144
PNG
(3-(3,5-Dimethyl-phenyl)-7-methyl-4-(1-methyl-piper...)
Show SMILES CN1CCCC(COc2c(-c3cc(C)cc(C)c3)c(=O)[nH]c3cc(C)ccc23)C1
Show InChI InChI=1S/C25H30N2O2/c1-16-7-8-21-22(13-16)26-25(28)23(20-11-17(2)10-18(3)12-20)24(21)29-15-19-6-5-9-27(4)14-19/h7-8,10-13,19H,5-6,9,14-15H2,1-4H3,(H,26,28)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.


Bioorg Med Chem Lett 9: 2615-20 (1999)


Article DOI: 10.1016/s0960-894x(99)00446-1
BindingDB Entry DOI: 10.7270/Q2TD9WK0
More data for this
Ligand-Target Pair