BDBM50082690 11-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-5-methyl-6-oxo-6,11-dihydro-5H-dibenzo[b,e]azepine-11-carbonitrile::CHEMBL142925

SMILES CN1c2ccccc2C(CCCN2CCC(O)(CC2)c2ccc(Cl)cc2)(C#N)c2ccccc2C1=O

InChI Key InChIKey=CBUFKJIVRCPPNA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082690   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082690(11-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-y...)
Affinity DataKi:  32nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082690(11-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-y...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of MIP-1-alpha-induced intracellular calcium mobilization in HEK293 cells expressing human CCR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed