BDBM50083912 2-(4-Ethynyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-3-one::CHEMBL366384

SMILES: O=c1n([nH]c2c1cnc1ccccc21)-c1ccc(cc1)C#C

InChI Key: InChIKey=ZNSSWFZNVYBLJJ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA-A receptor; alpha-2/beta-3/gamma-2 (Human)	BDBM50083912 (2-(4-Ethynyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Human)	BDBM50083912 (2-(4-Ethynyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM50083912 (2-(4-Ethynyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Human)	BDBM50083912 (2-(4-Ethynyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES Show InChI	GoogleScholar	UniChem		0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair