BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM50084275 7,7-Spiro analogue ofBuprinorphine::CHEMBL31605

SMILES: CO[C@]12C=CC3(CC11CCC(C)(C)[C@H]1O)C1Cc4ccc(O)c5O[C@H]2C3(CCN1C)c45

InChI Key:

Data: 3 KI 3 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084275
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Human)	BDBM50084275 (7,7-Spiro analogue ofBuprinorphine \| CHEMBL31605) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50084275 (7,7-Spiro analogue ofBuprinorphine \| CHEMBL31605) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50084275 (7,7-Spiro analogue ofBuprinorphine \| CHEMBL31605) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50084275 (7,7-Spiro analogue ofBuprinorphine \| CHEMBL31605) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50084275 (7,7-Spiro analogue ofBuprinorphine \| CHEMBL31605) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50084275 (7,7-Spiro analogue ofBuprinorphine \| CHEMBL31605) Show SMILES Show InChI	GoogleScholar	UniChem		8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair