BDBM50086102 1-[2-(5-Hydroxy-1H-indol-3-yl)-ethyl]-3-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-urea::CHEMBL15139

SMILES COc1ccc(NC(=O)NCCc2c[nH]c3ccc(O)cc23)cc1N1CCN(C)CC1

InChI Key InChIKey=FHMGXDNSPPUJTF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086102   

Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50086102(1-[2-(5-Hydroxy-1H-indol-3-yl)-ethyl]-3-[4-methoxy...)
Affinity DataIC50:  467nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50086102(1-[2-(5-Hydroxy-1H-indol-3-yl)-ethyl]-3-[4-methoxy...)
Affinity DataIC50:  57nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50086102(1-[2-(5-Hydroxy-1H-indol-3-yl)-ethyl]-3-[4-methoxy...)
Affinity DataIC50:  200nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed