BDBM50087016 8-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL281274::Ro65-6570

SMILES: O=C1NCN(c2ccccc2)C11CCN(CC1)C1Cc2cccc3cccc1c23

InChI Key: InChIKey=BBOAHBVXCYBKLC-UHFFFAOYSA-N

Data: 8 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50087016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
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Nociceptin receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
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Nociceptin receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nociceptin receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		12.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50087016 (Ro65-6570 | CHEMBL281274 | 8-Acenaphthen-1-yl-1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		302	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair